María José de Leone

Me encuentro terminando mis estudios de Tesis doctoral en relación al estudio de la regulación del reloj circadiano de Arabidopsis thaliana por señales ambientales.

Agrofoglio YC, Iglesias MJ, Perez-Santángelo S, de Leone MJ, Koester T, Catalá R, Salinas J, Yanovsky MJ, Staiger D, Mateos JL. Arginine methylation of SM-LIKE PROTEIN 4 antagonistically affects alternative splicing during Arabidopsis stress responses. The Plant Cell. 2024 May 29;36(6):2219-2237.https://doi.org/10.1093/plcell/koae051

de Leone MJ, Yanovsky MJ (2024). The Circadian Clock And Thermal Regulation In Plants: Novel Findings On The Role Of Positive Circadian Clock-Regulators In Temperature Responses. Journal of Experimental Botany. May 20;75(10):2809-2818 https://doi.org/10.1093/jxb/erae045

Careno DA, Assaf CH, Eggermont EDC, Canelo M, Cerdán PD, Yanovsky MJ. Role of Phytochromes in Red Light-Regulated Alternative Splicing in Arabidopsis thaliana: Impactful but Not Indispensable. Cells. 2023 12(20):2447. (2023) doi: 10.3390/cells12202447. PubMed

Lorenzo CD, García-Gagliardi P, Gobbini ML, Freytes SN, Antonietti MS, Mancini E, Dezar CA, Watson G, Yanovsky MJ, Cerdán PD. MsTFL1A delays flowering and regulates shoot architecture and root development in Medicago sativa. Plant Reprod. (2023 in Press). doi: 10.1007/s00497-023-00466-7.      PubMed

Mateos JL, Sanchez SE, Legris M, Esteve-Bruna D, Torchio JC, Petrillo E, Goretti D, Blanco-Touriñán N, Seymour DK, Schmid M, Weigel D, Alabadí D, Yanovsky MJ. PICLN modulates alternative splicing and light/temperature responses in plants. Plant Physiol. (2023). 191(2):1036-1051 doi: 10.1093/plphys/kiac527.      PubMed

Sorkin ML, Tzeng SC, King S, Romanowski A, Kahle N, Bindbeutel R, Hiltbrunner A, Yanovsky MJ, Evans BS, Nusinow DA. COLD REGULATED GENE 27 and 28 Antagonize the Transcriptional Activity of the RVE8/LNK1/LNK2 Circadian Complex. Plant Physiol. 192(3):2436-2456 (2023). doi: 10.1093/plphys/kiad210.      PubMed

Careno DA, Santangelo SP, Macknight RC, Yanovsky MJ. The 5'-3' mRNA Decay Pathway Modulates The Plant Circadian Network In Arabidopsis. Plant Cell Physiol. 63(11):1709-1719 (2022). doi: 10.1093/pcp/pcac126.      PubMed

Gonzalez Lopez Ledesma MM, Sanchez L, Ojeda DS, Oviedo Rouco S, Rossi AH, Varese A, Mazzitelli I, Pascuale CA, Miglietta EA, Rodríguez PE, Pallarés HM, Costa Navarro GS, Caramelo JJ, Rothlauf PW, Liu Z, Bloyet LM, Cornejo Pontelli M, Rasetto NB, Wenker SD, Ramis LY, Bialer MG, de Leone MJ, Hernando CE, Bianchimano L, Ríos AS, Treffinger Cienfuegos MS, Rodriguez García DR, Longueira Y, Laufer N, Alvarez D, Ceballos A, Ochoa V, Monzani C, Turk G, Salvatori M, Carradori J, Prost K, Rima A, Varela C, Ercole R, Toro RI, Gutierrez S, Zubieta M, Acuña D, Nabaes Jodar MS, Torres C, Mojsiejczuk L, Viegas M, Velazquez P, Testa C, Kreplak N, Yanovsky M, Whelan S, Geffner J, Pifano M, Gamarnik AV. Longitudinal Study after Sputnik V Vaccination Shows Durable SARS-CoV-2 Neutralizing Antibodies and Reduced Viral Variant Escape to Neutralization over Time. mBio. 13(1):e0344221 (2022). doi: 10.1128/mbio.03442-21.      PubMed

Mancini E, Ravinovich A, Iserte J, Yanovsky M, Chernomoretz A. ASpli: Integrative analysis of splicing landscapes through RNA-Seq assays. Bioinformatics. 37(17):2609-2616 (2021). doi: 10.1093/bioinformatics/btab141.      PubMed

 

Ojeda DS, Gonzalez Lopez Ledesma MM, Pallarés HM, Costa Navarro GS, Sanchez L, Perazzi B, Villordo SM, Alvarez DE; BioBanco Working Group, Echavarria M, Oguntuyo KY, Stevens CS, Lee B, Carradori J, Caramelo JJ, Yanovsky MJ, Gamarnik AV. Emergency response for evaluating SARS-CoV-2 immune status, seroprevalence and convalescent plasma in Argentina. PLoS Pathog. 17(1):e1009161 (2021). doi: 10.1371/journal.ppat.1009161.       PubMed

Romero-Montepaone S, Sellaro R, Hernando CE, Costigliolo-Rojas C, Bianchimano L, Ploschuk EL, Yanovsky MJ, Casal JJ. Functional convergence of growth responses to shade and warmth in Arabidopsis. New Phytol. 231(5):1890-1905 (2021). doi: 10.1111/nph.17430.      PubMed

Rossi AH, Ojeda DS, Varese A, Sanchez L, Gonzalez Lopez Ledesma MM, Mazzitelli I, Juliá AA, Rouco SO, Pallarés HM, Costa Navarro GS, Rasetto N, Garcia CI, Wenker SD, Ramis LY, Bialer MG, Jose de Leone M, Hernando CE, Sosa S, Bianchimano L, Rios A, Treffinger Cienfuegos MS, Caramelo JJ, Longueira Y, Laufer N, Alvarez D, Carradori J, Pedrozza D, Rima A, Echegoyen C, Ercole R, Gelpi P, Marchetti S, Zubieta M, Docena G, Kreplak N, Yanovsky M, Geffner J, Pifano M, Gamarnik AV. Sputnik V Vaccine Elicits Seroconversion and Neutralizing Capacity to SARS CoV-2 after a Single Dose. Cell Rep Med. 2(8):100359 (2021). doi: 10.1016/j.xcrm.2021.100359.      PubMed

Simonovich VA, Burgos Pratx LD, Scibona P, Beruto MV, Vallone MG, Vázquez C, Savoy N, Giunta DH, Pérez LG, Sánchez MDL, Gamarnik AV, Ojeda DS, Santoro DM, Camino PJ, Antelo S, Rainero K, Vidiella GP, Miyazaki EA, Cornistein W, Trabadelo OA, Ross FM, Spotti M, Funtowicz G, Scordo WE, Losso MH, Ferniot I, Pardo PE, Rodriguez E, Rucci P, Pasquali J, Fuentes NA, Esperatti M, Speroni GA, Nannini EC, Matteaccio A, Michelangelo HG, Follmann D, Lane HC, Belloso WH; PlasmAr Study Group; COVIDAR Argentina Consortium: Gonzalez Lopez Ledesma MM, Sanchez LN, Costa Navarro GS, Pallares HM, Villordo SM, Alvarez DE, Caramelo JJ, Carradori J, Yanovsky MJ. A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia. N Engl J Med. 384(7):619-629 (2021). doi: 10.1056/NEJMoa2031304.      PubMed      Clinical Trial

de Leone MJ, Hernando CE, Mora-García S, Yanovsky MJ. It's a matter of time: the role of transcriptional regulation in the circadian clock-pathogen crosstalk in plants. Transcription. 11(3-4):100-116 (2020). doi: 10.1080/21541264.2020.1820300.      PubMed

de Leone MJ, Hernando CE, Romanowski A, Careno DA, Soverna AF, Sun H, Bologna NG, Vázquez M, Schneeberger K, Yanovsky MJ. Bacterial Infection Disrupts Clock Gene Expression to Attenuate Immune Responses. Curr Biol. 30(9):1740-1747 (2020). doi: 10.1016/j.cub.2020.02.058.      PubMed