Genética y Fisiología Molecular English version

Katz MJ, Rodríguez F, Evangelisti F, Borrat AG, Pérez-Pandolfo S, Peters T, Sommario N, Boccaccio GL, Melani M, Wappner P. Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability. Nature Communications. 2025;16(1):5858. https://doi.org/10.1038/s41467-025-58389-y Research article  PubMed

 

Sorianello E, Katz MJ, Acevedo JM, Melani M, Pérez-Perri JI, Wappner P. The translational inhibitor 4EBP/Thor is required for Drosophila adaptation to hypoxia. Scientific Reports. 2025;15(1):23370. https://doi.org/10.1038/s41598-025-94457-5 Research article  PubMed

 

Suárez-Freire S, Pérez-Pandolfo S, Fresco SM, Valinoti J, Sorianello E, Wappner P, Melani M. The exocyst complex controls multiple events in the pathway of regulated exocytosis. eLife. 2024;12:RP92404. https://doi.org/10.7554/elife.92404   Research article  PubMed 

 

Aguilera MO, Robledo E, Melani M, Wappner P, Colombo M. FKBP8 is a novel molecule that participates in the regulation of the autophagic pathway. Biochimica et biophysica acta. Molecular cell research. 2022;1869(5):119212. https://doi.org/10.1016/j.bbamcr.2022.119212  Research article  PubMed

 

Valko A, Pérez-Pandolfo S, Sorianello E, Brech A, Wappner P, Melani M. Adaptation to hypoxia in Drosophila melanogaster requires autophagy. Autophagy. 2022;18(4):909-920. https://doi.org/10.1080/15548627.2021.1991191 Research article    PubMed

 

de la Riva-Carrasco R, Pérez-Pandolfo S, Freire SS, Romero NM, Bhujabal Z, Johansen T, Wappner P, Melani M. The immunophilin Zonda controls regulated exocytosis in endocrine and exocrine tissues. Traffic. 2021;22(4):111-122. https://doi.org/10.1111/tra.12777  Research article PubMed

 

Wappner P, Zurita M. The Latin American Society for Developmental Biology: A Successful History. The International Journal of Developmental Biology. 2021;65(1-2-3):77-81. https://doi.org/10.1387/ijdb.200019mz  Research article   PubMed

 

Blanco-Obregón DM, Katz MJ, Durrieu L, Gándara L, Wappner P. Context-specific functions of Notch in Drosophila blood cell progenitors. Developmental Biology. 2020;462(1):101-115. https://doi.org/10.1016/j.ydbio.2020.03.018  Research article  PubMed

 

Gándara L, Durrieu L, Behrensen C, Wappner P. A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation. Scientific Reports. 2019;9(1):19945.  https://doi.org/10.1038/s41598-019-56446-3  Research article PubMed

 

Gándara L, Wappner P. Metabo-Devo: A metabolic perspective of development. Mechanisms of Development. 2018;154:12-23. https://doi.org/10.1016/j.mod.2018.02.004  Review     PubMed      

 

Markolovic S, Zhuang Q, Wilkins SE, Eaton CD, Abboud MI, Katz MJ, McNeil HE, Le?niak RK, Hall C, Struwe WB, Konietzny R, Davis S, Yang M, Ge W, Benesch JLP, Kessler BM, Ratcliffe PJ, Cockman ME, Fischer R, Wappner P, Chowdhury R, Coleman ML, Schofield CJ. The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases. Nature Chemical Biology. 2018;14(7):688-695.  https://doi.org/10.1038/s41589-018-0071-y Research article      PubMed

 

Riesgo-Escovar JR, Mayor R, Wappner P, Yan I. MoD Special issue on "Developmental Biology in Latin America". Mechanisms of Development.  2018;154:1. https://doi.org/10.1016/j.mod.2018.11.003    Editorial   PubMed 

   

Melani M, Valko A, Romero NM, Aguilera MO, Acevedo JM, Bhujabal Z, Pérez-Perri J, de la Riva-Carrasco RV, Katz MJ, Sorianello E, D'Alessio C, Juhász G, Johansen T, Colombo MI, Wappner P. Zonda is a novel early component of the autophagy pathway in Drosophila. Molecular Biology of the Cell. 2017;28(22):3070-3081. https://doi.org/10.1091/mbc.e16-11-0767   Research article    PubMed

 

Bertolin AP, Katz MJ, Yano M, Pozzi B, Acevedo JM, Blanco-Obregón DM, Gándara L, Sorianello E, Kanda H, Okano H, Srebrow A, Wappner P. Musashi mediates translational repression of the Drosophila hypoxia inducible factor. Nucleic Acids Research. 2016;44:7555-7567.  https://doi.org/10.1093/nar/gkw372  Research article    PubMed

 

De Lella-Ezcurra AL, Bertolin AP, Kim K, Katz MJ, Gándara L, Misra T, Luschnig S, Perrimon N, Melani M, Wappner P. miR-190 enhances HIF-dependent responses to hypoxia in Drosophila by inhibiting the prolyl-4-hydroxylase fatiga. PLoS Genetics. 2016;12(5):e1006073. https://doi.org/10.1371/journal.pgen.1006073 Research article    PubMed