Borkosky SS, Peralta-Martínez R, Armella-Sierra A, Esperante SA, Lizárraga L, García-Pardo J, Ventura S, Sánchez IE, de Prat Gay G. Experimental kinetic mechanism of p53 condensation-amyloid aggregation. Biophysical Journal. 2025;124(10):1658-1673. https://doi.org/10.1016/j.bpj.2025.04.009  Research article PubMed

 

Borkosky SS, Fassolari M, Campos-León K, Rossi HA, Salgueiro M, Pascuale CA, Peralta-Martínez R, Gastón K, de Prat Gay G. Biomolecular condensation of the human papillomavirus E2 master regulator with p53: Implications in viral replication. Journal of Molecular Biology. 2023;435(16):167889. https://doi.org/10.1016/j.jmb.2022.167889   Research article PubMed

 

Salgueiro M, Camporeale G, Visentin A, Arán M, Pellizza L, Esperante SA, Corbat A, Grecco H, Sousa B, Esperón R, Borkosky SS, de Prat Gay G. Molten globule driven and self-downmodulated phase separation of a viral factory scaffold. Journal of Molecular Biology. 2023;435(16):168153. https://doi.org/10.1016/j.jmb.2023.168153    Research article PubMed

 

Armella-Sierra A, Loureiro ME, Esperante SA, Borkosky SS, Gallo GL, de Prat Gay G, López N. Nuclease activity of the Junín virus nucleoprotein C-terminal domain. Viruses. 2023;15(9):1818. https://doi.org/10.3390/v15091818 Research article  PubMed

 

Visentin A, Demitroff N, Salgueiro M, Borkosky SS, Uversky VN, Camporeale G, de Prat Gay G. Assembly of the tripartite and RNA condensates of the respiratory syncytial virus factory proteins in vitro: Role of the transcription antiterminator M2-1. Viruses. 2023;15(6):1329. https://doi.org/10.3390/v15061329  Research article   PubMed

 

Esperante SA, Alvarez-Paggi D, Salgueiro M, Desimone MF, de Oliveira GAP, Arán M, García-Prado J, Aptekmann AA, Ventura S, Alonso LG, de Prat Gay G. A finely tuned interplay between calcium binding, ionic strength and pH modulates conformational and oligomerization equilibria in the Respiratory Syncytial Virus Matrix (M) protein. Archives of Biochemistry and Biophysics. 2022;731:109424. https://doi.org/10.1016/j.abb.2022.109424  Research article PubMed

 

González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernández-Ballester G, Blanes-Mira C, Sánchez IE, de Prat Gay G, Cortés J, Bernadó P, Pappu RV, Holehouse AS, Daughdrill GW, Chemes LB. Conformational buffering underlies functional selection in intrinsically disordered protein regions. Nature Structural & Molecular Biology. 2022;29(8):781-790. https://doi.org/10.1038/s41594-022-00811-w  Research article PubMed

 

López N, Camporeale G, Salgueiro M, Borkosky SS, Visentín A, Peralta-Martínez R, Loureiro ME, de Prat Gay G. Deconstructing virus condensation. PLoS Pathogens. 2021;17(10):e1009926. https://doi.org/10.1371/journal.ppat.1009926  Review  PubMed

 

Leroy L, Barbosa JARG, de Prat Gay G, Polikarpov I, Pinheiro CB. The structure of the extended E2 DNA-binding domain of the bovine papillomavirus-1. Proteins. 2020;88(1):106-112.  https://doi.org/10.1002/prot.25773 Research article  PubMed

 

Álvarez-Paggi D, Esperante SA, Salgueiro M, Camporeale G, de Oliveira GAP, de Prat Gay G. A conformational switch balances viral RNA accessibility and protection in a nucleocapsid ring model. Archives of Biochemistry and Biophysics. 2019;671:77-86. https://doi.org/10.1016/j.abb.2019.06.005  Research article  PubMed

 

Álvarez-Paggi D, Lorenzo JR, Camporale G, Montero L, Sánchez IE, de Prat Gay G, Alonso LG. Topology dictates evolution of regulatory cysteines in a family of viral oncoproteins. Molecular Biology and Evolution. 2019;36(7):1521-1532. https://doi.org/10.1093/molbev/msz085 Comparative Study  PubMed

 

Conci J, Álvarez-Paggi D, de Oliveira GAP, Pagani TD, Esperante SA, Borkosky SS, Arán M, Alonso LG, Mohana-Borges R, de Prat-Gay G. Conformational isomerization involving conserved proline residues modulates oligomerization of the NS1 interferon response inhibitor from the syncytial respiratory virus. Biochemistry. 2019;58(26):2883-2892. https://doi.org/10.1021/acs.biochem.8b01288   Research article  PubMed

 

Leroy LMD, Barbosa JARG, de Prat Gay G, Polikarpov I, Pinheiro CB. The structure of the extended E2 DNA-binding domain of the Bovine Papillomavirus-1. Proteins. 2019;88(1):106-112. https://doi.org/10.1002/prot.25773       Research article PubMed

 

Esperante SA, Álvarez-Paggi D, Salgueiro M, de Prat Gay G. Mechanism of tetramer dissociation, unfolding, and oligomer assembly of Pneumovirus M2-1 transcription antiterminators. ACS Omega. 2018;3(11):14732-14745. https://doi.org/10.1021/acsomega.8b01600  Research article PubMed

 

Glavina J, Román EA, Espada R, de Prat Gay G, Chemes LB, Sánchez IE. Interplay between sequence, structure and linear motifs in the adenovirus E1A hub protein. Virology. 2018;525:117-131.    https://doi.org/10.1016/j.virol.2018.08.012   Research article  PubMed