Biología de Sistemas Integrativa English version

Chernomoretz A, Marsico F, Iserte J, Herrera Piñero M, Escobar MS, Balparda M, Sibilla G. Bayesian networks for DNA-based kinship analysis: Functionality and validation of the GENis missing person identification module. Forensic Sci Int: Genet Suppl Ser. 8:131-132 (2022). doi:10.1016/j.fsigss.2022.10.008

Danko D, et al; International MetaSUB Consortium. A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell. 184(13):3376-3393.e17 (2021). doi: 10.1016/j.cell.2021.05.002.      PubMed

Mancini E, Ravinovich A, Iserte J, Yanovsky M, Chernomoretz A. ASpli: Integrative analysis of splicing landscapes through RNA-Seq assays. Bioinformatics. 37(17):2609-2616 (2021). doi: 10.1093/bioinformatics/btab141.      PubMed

Chernomoretz A, Balpardad M, La Grutta L, Calabrese A, Martinez G, Escobard MS, Sibillad G. GENis, an open-source multi-tier forensic DNA information system. Forensic Science International. 2:100132 (2020).       DOI:10.1016/j.fsir.2020.100132

Urán Landaburu L, Berenstein AJ, Videla S, Maru P, Shanmugam D, Chernomoretz A, Agüero F. TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration. Nucleic Acids Res. 48(D1):D992-D1005 (2020). doi: 10.1093/nar/gkz999.      PubMed

Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Veroli GYD, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J, Chernomoretz A, et al. Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nat Commun. 10(1):2674 (2019). doi: 10.1038/s41467-019-09799-2.      PubMed

Altszyler E, Ventura AC, Colman-Lerner A, Chernomoretz A. Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations. PLoS One. 12(6):e0180083 (2017). doi: 10.1371/journal.pone.0180083.      PubMed

Mancini E, Iserte J, Yanovsky M, Chernomoretz A. ASpli: Analysis of alternative splicing using RNA-Seq. R package version 1.4.0. (2017). doi: 10.18129/B9.bioc.ASpli Software Packages

Palopoli N, Monzon AM, Parisi G, Chernomoretz A, Agüero F. A report on the “International Society for Computational Biology - Latin America (ISCB-LA)” Bioinformatics Conference 2016. EMBnet. J. 23:e883 (2017). doi: 10.14806/ej.23.0.883.    Report      DOI

Berenstein AJ, Magariños MP, Chernomoretz A, Agüero F. A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases. PLoS Negl Trop Dis. 10:e0004300 (2016). doi: 10.1371/journal.pntd.0004300.        PubMed

C, Ibañez IL, Berenstein A, Notcovich C, Cerda MB, Klamt F, Chernomoretz A, Durán H. Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated. Oncotarget. 7(27):41154-41171 (2016). doi: 10.18632/oncotarget.9273. PubMed

Piñero J, Berenstein A, Gonzalez-Perez A, Chernomoretz A, Furlong LI. Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing. Sci Rep. 6:24570 (2016). doi: 10.1038/srep24570.       PubMed

Berenstein AJ, Pinero J, Furlong LI, Chernomoretz A. Mining the modular structure of protein interaction networks. PLoS One. 10: e0122477 (2015). doi: 10.1371/journal.pone.0122477.      PubMed

Radice PD, Mathieu P, Leal MC, Farias MI, Ferrari C, Puntel M, Salibe M, Chernomoretz A, Pitossi FJ. Fibulin-2 is a key mediator of the pro-neurogenic effect of TGF-beta1 on adult neural stem cells. Mol Cell Neurosci. 67: 75-83 (2015). doi: 10.1016/j.mcn.2015.06.004.      PubMed

Schlaen RG, Mancini E, Sanchez SE, Perez Santangelo S, Rugnone ML, Simpson CG, Brown JW, Zhang X, Chernomoretz A, Yanovsky MJ. The spliceosome assembly factor GEMIN2 attenuates the effects of temperature on alternative splicing and circadian rhythms. Proc Natl Acad Sci U S A. 112: 9382-9387 (2015). doi: 10.1073/pnas.1504541112.      PubMed