Neurociencias
Ayelén Groisman
Ayelén Groisman obtuvo su Licenciatura en Cs. Biológicas en FCEN-UBA (2014). Recibió beca CIN (Consejo Interuniversitario Nacional) durante dos años consecutivos para realizar pasantía de investigación en el IFIBYNE con el director Dr. Osvaldo Uchitel durante los estudios de grado, obtuvo beca Iberoamérica para realizar parte de los estudios de grado en la Universidad de Valencia, España y premio al mérito académico Santander Río, reconocido por la Universidad de Buenos Aires. Fue seleccionada por la IBRO (International Brain Research Organization) para realizar pasantía de investigación en el laboratorio del Dr. Rusty Gage, Salk Institute San Diego USA, en el marco de su formación de doctorado. Actualmente es becaria doctoral CONICET en la Fundación Instituto Leloir bajo la dirección del Dr. Alejandro Schinder, su proyecto consiste en el estudio de la integración de neuronas nuevas en el circuito neurondel hipocampo adulto.
Rasetto NB, Giacomini D, Berardino AA, Waichman TV, Beckel MS, Di Bella DJ, Brown J, Davies-Sala MG, Gerhardinger C, Lie DC, Arlotta P, Chernomoretz A, Schinder AF. Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus. Science Advances. 2024;10(29):eadp6039. https://doi.org/10.1126/sciadv.adp6039 Research article PubMed
Waichman TV, Vercesi ML, Berardino AA, Beckel MS, Giacomini D, Rasetto NB, Herrero M, Di Bella DJ, Arlotta P, Schinder AF, Chernomoretz A. scX: a user-friendly tool for scRNAseq exploration. Bioinformatics Advances. 2024;4(1):vbae062. https://doi.org/10.1093/bioadv/vbae062 Research article PubMed
Groisman AI, Aguilar-Arredondo A, Giacomini D, Schinder AF. Neuroligin-2 controls the establishment of fast GABAergic transmission in adult-born granule cells. Hippocampus. 2023;33(4):424-441. https://doi.org/10.1002/hipo.23505 Research article PubMed
Mugnaini M, Trinchero MF, Schinder AF, Piatti VC, Kropff E. Unique potential of immature adult-born neurons for the remodeling of CA3 spatial maps. Cell Reports. 2023;42(9):113086. https://doi.org/10.1016/j.celrep.2023.113086 Report PubMed
Schinder AF. Alejandro Schinder. Neuron. 2021;109(19):3031-3033. https://doi.org/10.1016/j.neuron.2021.09.018 Q&As-Question and Answer PubMed
Trinchero MF, Giacomini D, Schinder AF. Dynamic interplay between GABAergic networks and developing neurons in the adult hippocampus. Current Opinion in Neurobiology. 2021;69:124-130. https://doi.org/10.1016/j.conb.2021.03.008 Review PubMed
Groisman AI, Yang SM, Schinder AF. Differential coupling of adult-born granule cells to Parvalbumin and Somatostatin interneurons. Cell Reports. 2020;30(1):202-214.e4. https://doi.org/10.1016/j.celrep.2019.12.005 Research article PubMed
Trinchero MF, Schinder AF. GABAergic interneurons control adult neurogenesis but astrocytes have the last word. Neuron. 2020;108(2):226-228. https://doi.org/10.1016/j.neuron.2020.09.041 Research article PubMed
Schinder AF, Trinchero MF, Groisman AI. Synaptogenesis in the adult CNS—Hippocampus. IN: Synapse development and maturation / John Rubenstein et al, ed. 1 st. ed., p.235-53. 2020. doi:10.1016/B978-0-12-823672-7.00010-7 Book Chapter
Bonafina A, Trinchero MF, Ríos AS, Bekinschtein P, Schinder AF, Paratcha G, Ledda F. GDNF and GFRα1 are required for proper integration of adult-born hippocampal neurons. Cell Reports. 2019;29(13):4308-4319.e4. https://doi.org/10.1016/j.celrep.2019.11.100 Research article PubMed
Terreros-Roncal J, Flor-García M, Moreno-Jiménez EP, Pallas-Bazarra N, Rábano A, Sah N, van Praag H, Giacomini D, Schinder AF, Ávila J, Llorens-Martín M. Activity-dependent reconnection of adult-born dentate granule cells in a mouse model of frontotemporal dementia. Journal of Neuroscience. 2019;39(29):5794-5815. https://doi.org/10.1523/jneurosci.2724-18.2019 Research article PubMed
Trinchero MF, Herrero M, Monzón-Salinas MC, Schinder AF. Experience-dependent structural plasticity of adult-born neurons in the aging hippocampus. Frontiers in Neuroscience. 2019;13:739. https://doi.org/10.3389/fnins.2019.00739 Research article PubMed
Trinchero MF, Herrero M, Schinder AF. Rejuvenating the brain with chronic exercise through adult neurogenesis. Frontiers in Neuroscience. 2019;13:1000. https://doi.org/10.3389/fnins.2019.01000 Research article PubMed
Kempermann G, Gage FH, Aigner L, Song H, Curtis MA, Thuret S, Kuhn HG, Jessberger S, Frankland PW, Cameron HA, Gould E, Hen R, Abrous DN, Toni N, Schinder AF, Zhao X, Lucassen PJ, Frisén J. Human adult neurogenesis: evidence and remaining questions. Cell Stem Cell. 2018;23(1):25-30. https://doi.org/10.1016/j.stem.2018.04.004 Review PubMed
Piatti VC, Schinder AF. Hippocampal mossy cells provide a fate switch for adult neural stem cells. Neuron. 2018;8;99(3):425-427. https://doi.org/10.1016/j.neuron.2018.07.044 Perspective PubMed