{"id":1340,"date":"2026-06-29T16:40:44","date_gmt":"2026-06-29T19:40:44","guid":{"rendered":"https:\/\/www.leloir.org.ar\/research\/?page_id=1340"},"modified":"2026-07-08T09:14:12","modified_gmt":"2026-07-08T12:14:12","slug":"behavioral-genetics","status":"publish","type":"page","link":"https:\/\/www.leloir.org.ar\/research\/behavioral-genetics\/","title":{"rendered":"behavioral genetics"},"content":{"rendered":"\n<div class=\"wp-block-stackable-spacer stk-block-spacer stk--no-padding stk-block stk-5bf724e\" data-block-id=\"5bf724e\"><style>.stk-5bf724e {height:20px !important;}<\/style><\/div>\n\n\n\n<div class=\"wp-block-greenshift-blocks-container alignfull gspb_container gspb_container-gsbp-c15c419\" id=\"gspb_container-id-gsbp-c15c419\">\n<div class=\"wp-block-greenshift-blocks-row gspb_row gspb_row-id-gsbp-18a8bbc\" id=\"gspb_row-id-gsbp-18a8bbc\"><div class=\"gspb_row__content\"> \n<div class=\"wp-block-greenshift-blocks-row-column gspb_row__col--6 gspb_row__col--xs-9 gspb_col-id-gsbp-1de9e8b\" id=\"gspb_col-id-gsbp-1de9e8b\">\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-fe81fce\" id=\"strong-research-area-strong\" data-block-id=\"fe81fce\"><style>.stk-fe81fce .stk-block-heading__text{color:var(--theme-palette-color-3, #a7a04d) !important;}@media screen and (max-width:689px){.stk-fe81fce {padding-bottom:0px !important;margin-bottom:0px !important;}}<\/style><h6 class=\"stk-block-heading__text has-text-color\"><strong>Research area<\/strong><\/h6><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-f5d6339\" id=\"strong-research-area-strong\" data-block-id=\"f5d6339\"><style>@media screen and (max-width:689px){.stk-f5d6339 {align-items:flex-start !important;padding-top:0px !important;padding-right:0px !important;padding-bottom:0px !important;padding-left:0px !important;margin-bottom:0px !important;display:flex !important;}}<\/style><h5 class=\"stk-block-heading__text has-text-align-left-mobile\"><strong><strong><strong><strong>Neuroscience<\/strong><\/strong><\/strong><\/strong><\/h5><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-greenshift-blocks-row-column gspb_row__col--6 gspb_row__col--xs-3 gspb_col-id-gsbp-643144c\" id=\"gspb_col-id-gsbp-643144c\">\n<div class=\"wp-block-stackable-image stk-block-image stk-block stk-aaae08c\" data-block-id=\"aaae08c\"><style>@media screen and (max-width:689px){.stk-aaae08c .stk-img-wrapper{width:80% !important;}}<\/style><figure><span class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-1066\" src=\"https:\/\/www.leloir.org.ar\/research\/wp-content\/uploads\/2026\/06\/neuro.png\" width=\"100\" height=\"100\"\/><\/span><\/figure><\/div>\n<\/div>\n <\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-stackable-columns alignfull stk-block-columns stk--hide-mobile stk-block stk-efbfbbe\" data-block-id=\"efbfbbe\"><style>.stk-efbfbbe {margin-bottom:0px !important;top:0px !important;left:0px !important;}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-efbfbbe-column alignfull\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-095be29 stk-block-background\" data-v=\"4\" data-block-id=\"095be29\"><style>.stk-095be29-container{margin-top:var(--stk--preset--spacing--none, 0px) !important;margin-right:var(--stk--preset--spacing--none, 0px) !important;margin-bottom:var(--stk--preset--spacing--none, 0px) !important;margin-left:var(--stk--preset--spacing--none, 0px) !important;min-height:var(--stk--preset--block-height--none, 0px) !important;}.stk-095be29 {align-self:center !important;background-color:var(--theme-palette-color-1, #164193) !important;border-top-right-radius:var(--stk--preset--border-radius--full, 9999px) !important;border-bottom-right-radius:var(--stk--preset--border-radius--full, 9999px) !important;border-bottom-left-radius:var(--stk--preset--border-radius--none, 0px) !important;overflow:hidden !important;min-height:var(--stk--preset--block-height--none, 0px) !important;align-items:center !important;max-width:350px !important;min-width:auto !important;padding-top:var(--stk--preset--spacing--none, 0px) !important;padding-bottom:var(--stk--preset--spacing--none, 0px) !important;padding-left:60px !important;margin-top:var(--stk--preset--spacing--none, 0px) !important;margin-left:0px !important;display:flex !important;}.stk-095be29:before{background-color:var(--theme-palette-color-1, #164193) !important;}@media screen and (min-width:690px){.stk-095be29 {flex:var(--stk-flex-grow, 1) 1 calc(56% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-095be29-container stk--no-background stk--no-padding\"><div class=\"has-text-align-left stk--block-horizontal-flex stk-block-content stk-inner-blocks stk-095be29-inner-blocks\">\n<div class=\"wp-block-stackable-columns stk-block-columns stk-block stk-a3b5388\" data-block-id=\"a3b5388\"><style>.stk-a3b5388 {padding-top:var(--stk--preset--spacing--none, 0px) !important;padding-right:0px !important;padding-bottom:var(--stk--preset--spacing--none, 0px) !important;}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-a3b5388-column\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-ec743fe\" data-v=\"4\" data-block-id=\"ec743fe\"><style>.stk-ec743fe {padding-left:var(--stk--preset--spacing--none, 0px) !important;margin-right:var(--stk--preset--spacing--none, 0px) !important;margin-left:var(--stk--preset--spacing--none, 0px) !important;}.stk-ec743fe-container{padding-left:var(--stk--preset--spacing--none, 0px) !important;}@media screen and (min-width:690px){.stk-ec743fe {flex:var(--stk-flex-grow, 1) 1 calc(66.667% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-ec743fe-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-ec743fe-inner-blocks\">\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-0108191\" id=\"strong-research-area-strong\" data-block-id=\"0108191\"><style>.stk-0108191 {margin-bottom:0px !important;}.stk-0108191 .stk-block-heading__text{color:var(--theme-palette-color-3, #a7a04d) !important;}<\/style><h6 class=\"stk-block-heading__text has-text-color\"><strong>Research area<\/strong><\/h6><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-0b4b126\" id=\"strong-neuroscience-strong\" data-block-id=\"0b4b126\"><style>.stk-0b4b126 {align-items:flex-start !important;padding-top:var(--stk--preset--spacing--none, 0px) !important;padding-bottom:var(--stk--preset--spacing--none, 0px) !important;margin-top:var(--stk--preset--spacing--none, 0px) !important;margin-bottom:var(--stk--preset--spacing--none, 0px) !important;margin-left:var(--stk--preset--spacing--none, 0px) !important;display:flex !important;}<\/style><h5 class=\"stk-block-heading__text\"><strong>Neuroscience<\/strong><\/h5><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-4110096\" data-v=\"4\" data-block-id=\"4110096\"><style>.stk-4110096 {align-self:center !important;padding-top:var(--stk--preset--spacing--none, 0px) !important;padding-right:var(--stk--preset--spacing--none, 0px) !important;padding-bottom:var(--stk--preset--spacing--none, 0px) !important;padding-left:var(--stk--preset--spacing--none, 0px) !important;margin-right:var(--stk--preset--spacing--none, 0px) !important;}.stk-4110096-inner-blocks{align-items:center !important;}@media screen and (min-width:690px){.stk-4110096 {flex:var(--stk-flex-grow, 1) 1 calc(33.333% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-4110096-container stk--no-background stk--no-padding\"><div class=\"stk--block-horizontal-flex stk--column-flex stk-block-content stk-inner-blocks stk-4110096-inner-blocks\">\n<div class=\"wp-block-stackable-image stk-block-image stk-block stk-5f46d71\" data-block-id=\"5f46d71\"><style>.stk-5f46d71 .stk-img-wrapper{width:100% !important;}<\/style><figure><span class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-1066\" src=\"https:\/\/www.leloir.org.ar\/research\/wp-content\/uploads\/2026\/06\/neuro.png\" width=\"100\" height=\"100\"\/><\/span><\/figure><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-9284d94\" data-v=\"4\" data-block-id=\"9284d94\"><style>@media screen and (min-width:690px){.stk-9284d94 {flex:var(--stk-flex-grow, 1) 1 calc(44% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-9284d94-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-9284d94-inner-blocks\"><\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-spacer stk-block-spacer stk--no-padding stk-block stk-e4a0b9e\" data-block-id=\"e4a0b9e\"><style>.stk-e4a0b9e {height:30px !important;}<\/style><\/div>\n\n\n\n<div class=\"wp-block-greenshift-blocks-row alignwide gspb_row gspb_row-id-gsbp-22b4991 gspb_row--gutter-20\" id=\"gspb_row-id-gsbp-22b4991\">\n<div class=\"wp-block-greenshift-blocks-row-column gspb_row__col--9 gspb_col-id-gsbp-c9b3f6b\" id=\"gspb_col-id-gsbp-c9b3f6b\">\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-104d4ac\" id=\"behavioral-genetics\" data-block-id=\"104d4ac\"><style>.stk-104d4ac {margin-bottom:40px !important;}.stk-104d4ac .stk-block-heading__text{color:var(--theme-palette-color-3, #a7a04d) !important;}<\/style><h2 class=\"stk-block-heading__text has-text-color\">BEHAVIORAL GENETICS<\/h2><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-41b44af\" id=\"strong-research-strong\" data-block-id=\"41b44af\"><style>.stk-41b44af .stk-block-heading__text{color:var(--theme-palette-color-1, #164193) !important;}<\/style><h3 class=\"stk-block-heading__text has-text-color\"><strong>Research<\/strong><\/h3><\/div>\n\n\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-bf578d0\" data-block-id=\"bf578d0\"><p class=\"stk-block-text__text\">Organisms have internal clocks that regulate their metabolism, physiology and behaviour to occur at optimal times throughout the day. These internal clocks allow them not only to anticipate but also to respond to the challenges they face. As an experimental model, we focus on the fruit fly Drosophila melanogaster, which has sleep\/wake cycles that deteriorate with age (as they do in humans). Our lab seeks to understand how brain clocks communicate with each other and with clocks in the rest of the body to stay synchronised. One such mechanism is the daily structural remodelling of their connectivity, which has revealed a degree of plasticity unexpected in the adult brain; dissecting the underlying molecular mechanisms could provide insights into the treatment of nervous system pathologies. Internal clocks also depend on complex molecular networks that integrate environmental and internal cues that are essential for maintaining homeostasis. We are investigating such integration between basal cellular metabolism and the molecular clock, and how its progressive dysfunction affects lifespan. To address this fundamental question, we are focusing on a gene essential for the regulation of lipid catabolism, whose dysfunction is associated with early developmental lethality.<\/p><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-bef9c0d\" id=\"strong-skills-amp-tools-strong\" data-block-id=\"bef9c0d\"><style>.stk-bef9c0d .stk-block-heading__text{color:var(--theme-palette-color-1, #164193) !important;}<\/style><h3 class=\"stk-block-heading__text has-text-color\"><strong>Skills &amp; tools<\/strong><\/h3><\/div>\n\n\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-6f973a4\" data-block-id=\"6f973a4\"><p class=\"stk-block-text__text\">We combine genetic approaches and behavioural analysis with molecular tools, immunohistochemical staining and confocal fluorescence microscopy to analyse the role of different molecules in the specific processes we are interested in. Specifically, we use genetic tools to perturb gene expression or the function of specific cell groups by expressing genetically encoded RNAs or probes. We take advantage of thermo- and chemogenetics coupled with calcium imaging as a proxy for neuronal activity to assess the consequences of different genetic interventions at different levels: at the cellular and network level through activity reporters, analysis of arborisation and cellular morphology; at the organismal level through behavioural assays. We have recently integrated a custom-built single objective light sheet microscope to monitor cellular remodelling in the intact animal.<\/p><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-8fb662c\" id=\"strong-collaboration-interests-strong\" data-block-id=\"8fb662c\"><style>.stk-8fb662c {margin-bottom:3px !important;}.stk-8fb662c .stk-block-heading__text{color:var(--theme-palette-color-1, #164193) !important;}<\/style><h3 class=\"stk-block-heading__text has-text-color\"><strong>Collaboration interests<\/strong><\/h3><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>RNA Sequencing (bulk, single cell, ATAC-Seq) on targeted populations<\/li>\n\n\n\n<li>Automatic segmentation of 3D EM volumes<\/li>\n\n\n\n<li>Lipidomics and proteomics<\/li>\n\n\n\n<li style=\"margin-bottom:24px\">Electrophysiology<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-fb4e260\" id=\"strong-selected-publications-strong\" data-block-id=\"fb4e260\"><style>.stk-fb4e260 {margin-bottom:3px !important;}.stk-fb4e260 .stk-block-heading__text{color:var(--theme-palette-color-1, #164193) !important;}<\/style><h3 class=\"stk-block-heading__text has-text-color\"><strong>Selected publications<\/strong><\/h3><\/div>\n\n\n\n<div class=\"wp-block-stackable-columns stk-block-columns stk-block stk-6b0f0e9\" data-block-id=\"6b0f0e9\"><style>.stk-6b0f0e9 {padding-left:0px !important;margin-bottom:var(--stk--preset--spacing--none, 0px) !important;}.stk-6b0f0e9-column{--stk-column-gap:var(--stk--preset--spacing--20, 0.44rem) !important;justify-content:flex-start !important;}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-6b0f0e9-column stk--flex\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-051e83d\" data-v=\"4\" data-block-id=\"051e83d\"><style>.stk-051e83d {min-height:var(--stk--preset--block-height--none, 0px) !important;max-width:1500px !important;min-width:auto !important;padding-left:var(--stk--preset--spacing--none, 0px) !important;margin-right:auto !important;margin-left:var(--stk--preset--spacing--none, 0px) !important;}@media screen and (min-width:690px){.stk-051e83d {flex:var(--stk-flex-grow, 1) 1 calc(82% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-051e83d-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-051e83d-inner-blocks\">\n<ul class=\"wp-block-list\">\n<li style=\"margin-left:0\">FERNANDEZ-ACOSTA, Magdalena, et al. orsai, the Drosophila homolog of human ETFRF1, links lipid catabolism to growth control. BMC biology, 2022, vol. 20, no 1, p. 233.<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-3edd196\" data-v=\"4\" data-block-id=\"3edd196\"><style>@media screen and (min-width:690px){.stk-3edd196 {flex:var(--stk-flex-grow, 1) 1 calc(18% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}@media screen and (max-width:689px){.stk-3edd196-container{margin-left:30px !important;}.stk-3edd196 {align-self:center !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-3edd196-container stk--no-background stk--no-padding\"><div class=\"has-text-align-left-mobile stk-block-content stk-inner-blocks stk-3edd196-inner-blocks\">\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-12c0695\" data-block-id=\"12c0695\"><div class=\"stk-row stk-inner-blocks stk-block-content stk-button-group\">\n<div class=\"wp-block-stackable-icon-button stk-block-icon-button stk-block stk-5f4831a\" data-block-id=\"5f4831a\"><style>.stk-5f4831a .stk-button{background:var(--theme-palette-color-1, #164193) !important;}.stk-5f4831a .stk-button:hover{background:var(--theme-palette-color-2, #312a74) !important;opacity:1 !important;}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/link.springer.com\/article\/10.1186\/s12915-022-01417-w\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 640 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M579.8 267.7c56.5-56.5 56.5-148 0-204.5c-50-50-128.8-56.5-186.3-15.4l-1.6 1.1c-14.4 10.3-17.7 30.3-7.4 44.6s30.3 17.7 44.6 7.4l1.6-1.1c32.1-22.9 76-19.3 103.8 8.6c31.5 31.5 31.5 82.5 0 114L422.3 334.8c-31.5 31.5-82.5 31.5-114 0c-27.9-27.9-31.5-71.8-8.6-103.8l1.1-1.6c10.3-14.4 6.9-34.4-7.4-44.6s-34.4-6.9-44.6 7.4l-1.1 1.6C206.5 251.2 213 330 263 380c56.5 56.5 148 56.5 204.5 0L579.8 267.7zM60.2 244.3c-56.5 56.5-56.5 148 0 204.5c50 50 128.8 56.5 186.3 15.4l1.6-1.1c14.4-10.3 17.7-30.3 7.4-44.6s-30.3-17.7-44.6-7.4l-1.6 1.1c-32.1 22.9-76 19.3-103.8-8.6C74 372 74 321 105.5 289.5L217.7 177.2c31.5-31.5 82.5-31.5 114 0c27.9 27.9 31.5 71.8 8.6 103.9l-1.1 1.6c-10.3 14.4-6.9 34.4 7.4 44.6s34.4 6.9 44.6-7.4l1.1-1.6C433.5 260.8 427 182 377 132c-56.5-56.5-148-56.5-204.5 0L60.2 244.3z\"\/><\/svg><\/div><\/span><\/a><\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-divider alignfull stk-block-divider stk--hide-desktop has-text-align-center stk-block stk-915f821\" data-block-id=\"915f821\"><style>.stk-915f821 hr.stk-block-divider__hr{background:#abb8c3 !important;}@media screen and (max-width:689px){.stk-915f821 {align-items:center !important;margin-bottom:0px !important;display:flex !important;}}<\/style><hr class=\"stk-block-divider__hr\"\/><\/div>\n\n\n\n<div class=\"wp-block-stackable-columns stk-block-columns stk-block stk-bf15457\" data-block-id=\"bf15457\"><style>.stk-bf15457 {padding-left:0px !important;margin-bottom:var(--stk--preset--spacing--none, 0px) !important;}.stk-bf15457-column{--stk-column-gap:var(--stk--preset--spacing--20, 0.44rem) !important;justify-content:flex-start !important;}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-bf15457-column stk--flex\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-82616a0\" data-v=\"4\" data-block-id=\"82616a0\"><style>.stk-82616a0 {min-height:var(--stk--preset--block-height--none, 0px) !important;max-width:1500px !important;min-width:auto !important;padding-left:var(--stk--preset--spacing--none, 0px) !important;margin-right:auto !important;margin-left:var(--stk--preset--spacing--none, 0px) !important;}@media screen and (min-width:690px){.stk-82616a0 {flex:var(--stk-flex-grow, 1) 1 calc(82% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-82616a0-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-82616a0-inner-blocks\">\n<ul class=\"wp-block-list\">\n<li style=\"margin-left:0\">DUHART, Jos\u00e9 M., et al. Circadian structural plasticity drives remodeling of E cell output. Current Biology, 2020, vol. 30, no 24, p. 5040-5048. e5.<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-8f43baf\" data-v=\"4\" data-block-id=\"8f43baf\"><style>@media screen and (min-width:690px){.stk-8f43baf {flex:var(--stk-flex-grow, 1) 1 calc(18% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}@media screen and (max-width:689px){.stk-8f43baf-container{margin-left:30px !important;}.stk-8f43baf {align-self:center !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-8f43baf-container stk--no-background stk--no-padding\"><div class=\"has-text-align-left-mobile stk-block-content stk-inner-blocks stk-8f43baf-inner-blocks\">\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-361a94b\" data-block-id=\"361a94b\"><div class=\"stk-row stk-inner-blocks stk-block-content stk-button-group\">\n<div class=\"wp-block-stackable-icon-button stk-block-icon-button stk-block stk-b97f828\" data-block-id=\"b97f828\"><style>.stk-b97f828 .stk-button{background:var(--theme-palette-color-1, #164193) !important;}.stk-b97f828 .stk-button:hover{background:var(--theme-palette-color-2, #312a74) !important;opacity:1 !important;}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(20)31427-5\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 640 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M579.8 267.7c56.5-56.5 56.5-148 0-204.5c-50-50-128.8-56.5-186.3-15.4l-1.6 1.1c-14.4 10.3-17.7 30.3-7.4 44.6s30.3 17.7 44.6 7.4l1.6-1.1c32.1-22.9 76-19.3 103.8 8.6c31.5 31.5 31.5 82.5 0 114L422.3 334.8c-31.5 31.5-82.5 31.5-114 0c-27.9-27.9-31.5-71.8-8.6-103.8l1.1-1.6c10.3-14.4 6.9-34.4-7.4-44.6s-34.4-6.9-44.6 7.4l-1.1 1.6C206.5 251.2 213 330 263 380c56.5 56.5 148 56.5 204.5 0L579.8 267.7zM60.2 244.3c-56.5 56.5-56.5 148 0 204.5c50 50 128.8 56.5 186.3 15.4l1.6-1.1c14.4-10.3 17.7-30.3 7.4-44.6s-30.3-17.7-44.6-7.4l-1.6 1.1c-32.1 22.9-76 19.3-103.8-8.6C74 372 74 321 105.5 289.5L217.7 177.2c31.5-31.5 82.5-31.5 114 0c27.9 27.9 31.5 71.8 8.6 103.9l-1.1 1.6c-10.3 14.4-6.9 34.4 7.4 44.6s34.4 6.9 44.6-7.4l1.1-1.6C433.5 260.8 427 182 377 132c-56.5-56.5-148-56.5-204.5 0L60.2 244.3z\"\/><\/svg><\/div><\/span><\/a><\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-divider alignfull stk-block-divider stk--hide-desktop has-text-align-center stk-block stk-fafee08\" data-block-id=\"fafee08\"><style>.stk-fafee08 hr.stk-block-divider__hr{background:#abb8c3 !important;}@media screen and (max-width:689px){.stk-fafee08 {align-items:center !important;margin-bottom:0px !important;display:flex !important;}}<\/style><hr class=\"stk-block-divider__hr\"\/><\/div>\n\n\n\n<div class=\"wp-block-stackable-columns stk-block-columns stk-block stk-a2d56a6\" data-block-id=\"a2d56a6\"><style>.stk-a2d56a6 {padding-left:0px !important;margin-bottom:var(--stk--preset--spacing--none, 0px) !important;}.stk-a2d56a6-column{--stk-column-gap:var(--stk--preset--spacing--20, 0.44rem) !important;justify-content:flex-start !important;}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-a2d56a6-column stk--flex\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-4b33d14\" data-v=\"4\" data-block-id=\"4b33d14\"><style>.stk-4b33d14 {min-height:var(--stk--preset--block-height--none, 0px) !important;max-width:1500px !important;min-width:auto !important;padding-left:var(--stk--preset--spacing--none, 0px) !important;margin-right:auto !important;margin-left:var(--stk--preset--spacing--none, 0px) !important;}@media screen and (min-width:690px){.stk-4b33d14 {flex:var(--stk-flex-grow, 1) 1 calc(82% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-4b33d14-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-4b33d14-inner-blocks\">\n<ul class=\"wp-block-list\">\n<li style=\"margin-left:0\">HERRERO, Anastasia, et al. Coupling neuropeptide levels to structural plasticity in Drosophila clock neurons. Current Biology, 2020, vol. 30, no 16, p. 3154-3166. e4<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-84af16c\" data-v=\"4\" data-block-id=\"84af16c\"><style>@media screen and (min-width:690px){.stk-84af16c {flex:var(--stk-flex-grow, 1) 1 calc(18% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}@media screen and (max-width:689px){.stk-84af16c-container{margin-left:30px !important;}.stk-84af16c {align-self:center !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-84af16c-container stk--no-background stk--no-padding\"><div class=\"has-text-align-left-mobile stk-block-content stk-inner-blocks stk-84af16c-inner-blocks\">\n<div class=\"wp-block-stackable-button-group stk-block-button-group stk-block stk-ffe44e6\" data-block-id=\"ffe44e6\"><div class=\"stk-row stk-inner-blocks stk-block-content stk-button-group\">\n<div class=\"wp-block-stackable-icon-button stk-block-icon-button stk-block stk-4553922\" data-block-id=\"4553922\"><style>.stk-4553922 .stk-button{background:var(--theme-palette-color-1, #164193) !important;}.stk-4553922 .stk-button:hover{background:var(--theme-palette-color-2, #312a74) !important;opacity:1 !important;}<\/style><a class=\"stk-link stk-button stk--hover-effect-darken\" href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(20)30825-3\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 640 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M579.8 267.7c56.5-56.5 56.5-148 0-204.5c-50-50-128.8-56.5-186.3-15.4l-1.6 1.1c-14.4 10.3-17.7 30.3-7.4 44.6s30.3 17.7 44.6 7.4l1.6-1.1c32.1-22.9 76-19.3 103.8 8.6c31.5 31.5 31.5 82.5 0 114L422.3 334.8c-31.5 31.5-82.5 31.5-114 0c-27.9-27.9-31.5-71.8-8.6-103.8l1.1-1.6c10.3-14.4 6.9-34.4-7.4-44.6s-34.4-6.9-44.6 7.4l-1.1 1.6C206.5 251.2 213 330 263 380c56.5 56.5 148 56.5 204.5 0L579.8 267.7zM60.2 244.3c-56.5 56.5-56.5 148 0 204.5c50 50 128.8 56.5 186.3 15.4l1.6-1.1c14.4-10.3 17.7-30.3 7.4-44.6s-30.3-17.7-44.6-7.4l-1.6 1.1c-32.1 22.9-76 19.3-103.8-8.6C74 372 74 321 105.5 289.5L217.7 177.2c31.5-31.5 82.5-31.5 114 0c27.9 27.9 31.5 71.8 8.6 103.9l-1.1 1.6c-10.3 14.4-6.9 34.4 7.4 44.6s34.4 6.9 44.6-7.4l1.1-1.6C433.5 260.8 427 182 377 132c-56.5-56.5-148-56.5-204.5 0L60.2 244.3z\"\/><\/svg><\/div><\/span><\/a><\/div>\n<\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-divider alignfull stk-block-divider stk--hide-desktop has-text-align-center stk-block stk-d22cf02\" data-block-id=\"d22cf02\"><style>.stk-d22cf02 hr.stk-block-divider__hr{background:#abb8c3 !important;}@media screen and (max-width:689px){.stk-d22cf02 {align-items:center !important;margin-bottom:0px !important;display:flex !important;}}<\/style><hr class=\"stk-block-divider__hr\"\/><\/div>\n\n\n\n<div class=\"wp-block-stackable-spacer stk-block-spacer stk--no-padding stk-block stk-a00a56c\" data-block-id=\"a00a56c\"><style>.stk-a00a56c {height:30px !important;}<\/style><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-greenshift-blocks-row-column gspb_row__col--3 gspb_col-id-gsbp-f78c24f\" id=\"gspb_col-id-gsbp-f78c24f\">\n<div class=\"wp-block-stackable-image stk-block-image stk-block stk-f475dab\" data-block-id=\"f475dab\"><style>.stk-f475dab .stk-img-wrapper{width:80% !important;}<\/style><figure><span class=\"stk-img-wrapper stk-image--shape-stretch\"><img loading=\"lazy\" decoding=\"async\" class=\"stk-img wp-image-1342\" src=\"https:\/\/www.leloir.org.ar\/research\/wp-content\/uploads\/2026\/06\/Fil__Ceriani1.png\" width=\"400\" height=\"400\" srcset=\"https:\/\/www.leloir.org.ar\/research\/wp-content\/uploads\/2026\/06\/Fil__Ceriani1.png 400w, https:\/\/www.leloir.org.ar\/research\/wp-content\/uploads\/2026\/06\/Fil__Ceriani1-300x300.png 300w, https:\/\/www.leloir.org.ar\/research\/wp-content\/uploads\/2026\/06\/Fil__Ceriani1-150x150.png 150w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/span><\/figure><\/div>\n\n\n\n<div class=\"wp-block-stackable-text stk-block-text stk-block stk-b236174\" data-block-id=\"b236174\"><style>.stk-b236174 {margin-bottom:0px !important;}<\/style><p class=\"stk-block-text__text\"><span style=\"color: #ffffff;\" class=\"stk-highlight\">Principal investigator<\/span><\/p><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-c6eea5f\" id=\"m-fernanda-ceriani-ph-d\" data-block-id=\"c6eea5f\"><style>.stk-c6eea5f .stk-block-heading__text{line-height:1.2em !important;}<\/style><h4 class=\"stk-block-heading__text\">M. Fernanda Ceriani, PhD<\/h4><\/div>\n\n\n\n<div class=\"wp-block-stackable-icon-label stk-block-icon-label stk-block stk-920abd0\" data-block-id=\"920abd0\"><style>.stk-920abd0 .stk-inner-blocks{gap:10px !important;}<\/style><div class=\"stk-row stk-inner-blocks stk-block-content\">\n<div class=\"wp-block-stackable-icon stk-block-icon has-text-align-left stk-block stk-dd29c01\" data-block-id=\"dd29c01\"><style>.stk-dd29c01 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:22px !important;width:22px !important;}.stk-dd29c01 .stk--svg-wrapper .stk--inner-svg svg:last-child, .stk-dd29c01 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g, path, rect, polygon, ellipse){fill:var(--theme-palette-color-5, #35b6b4) !important;}<\/style><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-dd29c01\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-dd-29-c-01-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-dd-29-c-01-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M64 112c-8.8 0-16 7.2-16 16v22.1L220.5 291.7c20.7 17 50.4 17 71.1 0L464 150.1V128c0-8.8-7.2-16-16-16H64zM48 212.2V384c0 8.8 7.2 16 16 16H448c8.8 0 16-7.2 16-16V212.2L322 328.8c-38.4 31.5-93.7 31.5-132 0L48 212.2zM0 128C0 92.7 28.7 64 64 64H448c35.3 0 64 28.7 64 64V384c0 35.3-28.7 64-64 64H64c-35.3 0-64-28.7-64-64V128z\"\/><\/svg><\/div><\/span><\/div>\n\n\n\n<div class=\"wp-block-stackable-heading stk-block-heading stk-block-heading--v2 stk-block stk-7b80074\" id=\"a-href-mailto-fceriani-leloir-org-ar-fceriani-leloir-org-ar-a\" data-block-id=\"7b80074\"><style>.stk-7b80074 .stk-block-heading__text{font-size:1.2rem !important;color:var(--theme-palette-color-5, #35b6b4) !important;}@media screen and (max-width:999px){.stk-7b80074 .stk-block-heading__text{font-size:1.2rem !important;}}<\/style><p class=\"stk-block-heading__text has-text-color\"><a href=\"mailto:fceriani@leloir.org.ar\">fceriani@leloir.org.ar<\/a><\/p><\/div>\n<\/div><\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<div class=\"wp-block-stackable-columns stk-block-columns stk-block stk-a0e1fa3\" data-block-id=\"a0e1fa3\"><div class=\"stk-row stk-inner-blocks stk-block-content stk-content-align stk-a0e1fa3-column\">\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-8ec3b2b\" data-v=\"4\" data-block-id=\"8ec3b2b\"><style>@media screen and (min-width:690px){.stk-8ec3b2b {flex:var(--stk-flex-grow, 1) 1 calc(20% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-8ec3b2b-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-8ec3b2b-inner-blocks\">\n<div class=\"wp-block-stackable-icon stk-block-icon stk-block stk-cacdf15\" data-block-id=\"cacdf15\"><style>.stk-cacdf15 .stk--svg-wrapper .stk--inner-svg svg:last-child{height:18px !important;width:18px !important;}.stk-cacdf15 .stk--svg-wrapper .stk--inner-svg svg:last-child, .stk-cacdf15 .stk--svg-wrapper .stk--inner-svg svg:last-child :is(g, path, rect, polygon, ellipse){fill:var(--theme-palette-color-3, #a7a04d) !important;}<\/style><span class=\"stk--svg-wrapper\"><div class=\"stk--inner-svg\"><svg style=\"height:0;width:0\"><defs><linearGradient id=\"linear-gradient-cacdf15\" x1=\"0\" x2=\"100%\" y1=\"0\" y2=\"0\"><stop offset=\"0%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-cacdf-15-color-1)\"><\/stop><stop offset=\"100%\" style=\"stop-opacity:1;stop-color:var(--linear-gradient-cacdf-15-color-2)\"><\/stop><\/linearGradient><\/defs><\/svg><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 512 512\" aria-hidden=\"true\" width=\"32\" height=\"32\"><path d=\"M336 352c97.2 0 176-78.8 176-176S433.2 0 336 0S160 78.8 160 176c0 18.7 2.9 36.8 8.3 53.7L7 391c-4.5 4.5-7 10.6-7 17v80c0 13.3 10.7 24 24 24h80c13.3 0 24-10.7 24-24V448h40c13.3 0 24-10.7 24-24V384h40c6.4 0 12.5-2.5 17-7l33.3-33.3c16.9 5.4 35 8.3 53.7 8.3zM376 96a40 40 0 1 1 0 80 40 40 0 1 1 0-80z\"\/><\/svg><\/div><\/span><\/div>\n<\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-stackable-column stk-block-column stk-column stk-block stk-0ccde29\" data-v=\"4\" data-block-id=\"0ccde29\"><style>@media screen and (min-width:690px){.stk-0ccde29 {flex:var(--stk-flex-grow, 1) 1 calc(80% - var(--stk-column-gap, 0px) * 1 \/ 2 ) !important;}}<\/style><div class=\"stk-column-wrapper stk-block-column__content stk-container stk-0ccde29-container stk--no-background stk--no-padding\"><div class=\"stk-block-content stk-inner-blocks stk-0ccde29-inner-blocks\">\n<ul style=\"padding-right:0;padding-left:0\" class=\"wp-block-list\">\n<li class=\"has-palette-color-3-color has-text-color has-link-color wp-elements-9c367cf97a49d330a22dee52fbf3ad99\" style=\"line-height:1.3\">circadian rhythms<br><\/li>\n\n\n\n<li class=\"has-palette-color-3-color has-text-color has-link-color wp-elements-c2056f7083c64bd893d7b2525f9efe72\" style=\"line-height:1.3\">neuronal plasticity<br><\/li>\n\n\n\n<li class=\"has-palette-color-3-color has-text-color has-link-color wp-elements-a5169fe68019761641859635a18f1779\" style=\"line-height:1.3\">Drosophila melanogaster<br><\/li>\n\n\n\n<li class=\"has-palette-color-3-color has-text-color has-link-color wp-elements-94855bee101c0e8ef84d6cda47737bd9\" style=\"line-height:1.3\">lipid metabolism<br><\/li>\n\n\n\n<li class=\"has-palette-color-3-color has-text-color has-link-color wp-elements-b12f9bcf806972758b623a6bde38ff37\" style=\"line-height:1.3\">aging<\/li>\n<\/ul>\n<\/div><\/div><\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Research area Neuroscience<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_gspb_post_css":"#gspb_row-id-gsbp-22b4991{justify-content:space-between;margin-top:0;display:flex;flex-wrap:wrap;margin-bottom:0;margin-left:0;padding-left:0}#gspb_row-id-gsbp-22b4991>.gspb_row__content{display:flex;justify-content:space-between;margin:0 auto;width:100%;flex-wrap:wrap}div[id^=gspb_col-id]{box-sizing:border-box;position:relative;padding:var(--gs-row-column-padding, 15px min(3vw, 20px))}#gspb_col-id-gsbp-c9b3f6b.gspb_row__col--9{width:calc(75% - 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