Virología Molecular
Jefe de Laboratorio: Dra. Andrea Gamarnik
Publicaciones
Filomatori, C.V., Iglesias, N.G., Villordo, S.M., Alvarez, D.E., Gamarnik, A.V. RNA sequences and structures required for the recruitment and activity of the dengue virus polymerase. J Biol Chem. (en prensa). PubMed
Villordo, S.M., Alvarez, D.E., Gamarnik, A.V. A balance between circular and linear forms of the dengue virus genome is crucial for viral replication. RNA. 16: 2325-2335 (2010). PubMed
Kaptein, S.J., De Burghgraeve, T., Froeyen, M., Pastorino, B., Alen, M.M., Mondotte, J.A., Herdewijn, P., Jacobs, M., de Lamballerie, X., Schols, D., Gamarnik, A.V., Sztaricskai, F., Neyts, J. A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro. Antimicrob Agents Chemother. 54: 5269-5280 (2010). PubMed
Samsa, M.M., Mondotte, J.A., Iglesias, N.G., Assunção-Miranda, I., Barbosa-Lima, G., Da Poian, A.T., Bozza, P.T., Gamarnik, A.V. Dengue virus capsid protein usurps lipid droplets for viral particle formation. PLoS Pathog. 5:e1000632 (2009) PubMed
Lodeiro, M.F., Filomatori, C.V., Gamarnik, A.V. Structural and functional studies of the promoter element for dengue virus RNA replication. J Virol. 83:993-1008 (2009). PubMed
Villordo, S.M., Gamarnik, A.V. Genome cyclization as strategy for flavivirus RNA replication. Virus Res. 139:230-239 (2009). Review PubMed
Alvarez, D.E., Filomatori, C.V., Gamarnik, A.V. Functional analysis of dengue virus cyclization sequences located at the 5 ' and 3 ' UTRs. Virology. 375:223-235 (2008). PubMed
Mondotte, J.A., Lozach, P.Y., Amara A., Gamarnik, A.V. Essential role of dengue virus envelope protein N glycosylation at asparagine-67 during viral propagation. J Virol. 81:7136-7148 (2007). PubMed
Alvarez, D., Lodeiro, M.F., Filomatori, C., Fucito, S., Mondotte, J. Gamarnik, A. Structural and functional análisis of dengue virus RNA. Novartis Found. Symp. 277:120-132 (2006). Review PubMed
Filomatori, C.V., Lodeiro, M.F., Álvarez, D.E., Samsa, M.M., Pietrasanta, L., Gamarnik, A.V. A 5’ RNA Element Promotes Dengue Virus RNA Synthesis on a Circular Genome. Gene Dev. 20: 2238-2249 (2006). PubMed
Melino, S., Fucito, S., Campagna, A., Wrubl, F., Gamarnik, A., Cicero, D., Paci, M. The active essential CFNS3d protein complex. FEBS J. 273: 3650-3662 (2006). PubMed
Gamarnik, A., Andino, R. Exploring RNA virus replication in Xenopus Oocytes. IN: Xenopus Protocols. Methods Mol. Biol. 322: 367-78 (2006). Review PubMed
Álvarez, D.E., Lodeiro, M.F., Ludueña, S.J., Pietrasanta, L.I., Gamarnik, A.V. Long-range RNA-RNA interactions circularize the dengue virus genome. J. Virol. 79: 6631-6643 (2005). PubMed
Czibener, C., Alvarez, D.E., Scodeller, E., Gamarnik, A.V. Characterization of internal ribosomal entry sites of Triatoma virus. J. Gen. Virol. 86: 2275-2280 (2005). PubMed
Álvarez, D.E., Lella Ezcurra, A.L. de, Fucito, S., Gamarnik, A.V. Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication. Virology 339: 200-212 (2005). PubMed