Terapia Molecular y Celular
Jefe de Laboratorio: Dr. Osvaldo L. Podhajcer
Publicaciones
Aquino, J.B., Bolontrade, M.F., García, M.G., Podhajcer, O.L., Mazzolini, G.M. Mesenchymal stem cells as therapeutic tools and gene carriers in liver fibrosis and hepatocellular carcinoma. Gene Ther. 17: 692-708 (2010). PubMed
Atorrasagati, C., Malvicini, M., Aquino, J.B., Alaniz, L., García, M., Rizzo, M., Bolontrade, M., Podhajcer, O.L., Mazzolini, G. Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells. Int J Cancer. 126: 2726-2740 (2010). PubMed
Llera, A.S., Girotti, M.R., Benedetti, L.G., Podhajcer, O.L. Matricellular proteins and inflammatory cells: A task force to promote or defeat cancer?. Cytokine Growth Factor Rev. 21: 67-76 (2010). PubMed
Podhajcer, O.L., Miriuka, S. Stem cell research in South America coming of age. Cell Stem Cell. 6: 209-213 (2010). PubMed
Alvarez, M.J., Salibe, M.C., Stolovitzky, G., Rubinstein, M., Pitossi, F.J., Podhajcer, O,L. Distal tumors elicit distinctive gene expression changes in mouse brain, different from those induced by arthtritis. Open Neurosc J. 3: 13-25 (2009). doi:10.2174/1874082000903010013
Cafferata, E.G., Maccio, D.R., López, M.V., Viale, D.L., Carbone, C., Mazzolini, G., Podhajcer O.L. A Novel A33-Promoter Based Conditional Replicative Adenovirus Suppresses Tumor Growth and Eradicates Hepatic Metastases in Human Colon Cancer models. Clin Cancer Res. 15: 3037-3049 (2009). PubMed
López, M.V., Viale, D.L., Cafferatta, E.G., Bravo, A.I., Carbone, C., Gould, D., Chernajovsky, Y., Podhajcer, O.L. Tumor associated stromal cells play a critical role on the outcome of the oncolytic efficacy of conditionally replicative adenoviruses. PLoS One. 4: e5119 (2009). PubMed
Policastro, L.L., Ibañez, I.L., Duran, H.A., Soria, G., Gottifredi, V., Podhajcer, O.L. Suppression of cancer growth by nonviral gene therapy based on a novel reactive oxygen species-responsive promoter. Mol Ther. 17: 1355-1364 (2009). PubMed