Biología Celular del RNA
Jefe de Laboratorio: Dra. Graciela L. Boccaccio
Publicaciones
Martínez Tosar, L.J., Thomas, M.G., Baez, M.V., Ibañez, I.L.,Chernomoretz, A., Boccaccio,G.L. The double-stranded RNA binding protein Staufen: from embryo polarity to the stress response and neurodegeneration. Front Biosci. (En prensa).
Thomas M.G., Loschi M., Desbats M.A., Boccaccio G.L. RNA granules: the good, the bad and the ugly. Cell Signal. 23:324-334 (2011). PubMed
Dekanty, A., Romero, N.M., Bertolin, A.P., Thomas, M.G., Leishman, C.C., Perez-Perri, J.I., Boccaccio, G.L., Wappner, P. Drosophila genome-wide RNAi screen identifies multiple regulators of HIF-dependent transcription in hypoxia. PLoS Genet. 6: 1000994 (2010). PubMed
Abrahamyan, L.G., Chatel-Chaix, L., Ajamian, L., Milev, M.P., Monette, A., Clément, J.F., Song, R., Lehmann, M., DesGroseillers, L., Laughrea, M., Boccaccio, G., Mouland, A.J. Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA. J Cell Sci. 123: 369-383 (2010). PubMed
Loschi, M., Leishman, C.C., Berardone, N., Boccaccio, G.L. Dynein and kinesin regulate stress-granule and P-body dynamics. J Cell Sci. 122: 3973-3982 (2009). PubMed
Thomas, M.G., Martínez Tosar, L.J., Desbats, M.A., Leishman, C.C., Boccaccio, G.L. Mammalian Staufen 1 is recruited to stress granules and impairs their assembly. J Cell Sci. 122: 563-573 (2009). PubMed
Báez, M.V., Boccaccio, G.L. Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules. J Biol Chem. 280: 43131-4340 (2005). PubMed
Craig, P.O., Berguer, P.M., Ainciart, N., Zylberman, V., Thomas, M.G., Martínez Tosar, L.J., Bulloj, A., Boccaccio, G.L., Goldbaum, F.A. Multiple display of a protein domain on a bacterial polymeric scaffold. Proteins. 61: 1089-1100 (2005). PubMed
Thomas, M.G., Martínez Tosar, L.J., Loschi, M., Pasquini, J.M., Correale, J., Kindler, S., Boccaccio, G.L. Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes. Mol Biol Cell. 16: 405-420 (2005). PubMed